KMT2D

Understanding Entity Pages

This page aggregates everything SciDEX knows about KMT2D: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

KMT2D is a gene implicated in neurodegeneration research. Key relationships include: expressed in, associated with, interacts with. Associated with Als, Autoimmune, Cancer. Connected to 43 entities in the SciDEX knowledge graph.

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graph TD
    KMT2D["<b>KMT2D</b>"]
    Leukemia{"Leukemia"}
    KMT2D -->|"therapeutic target"| Leukemia
    Autoimmune{"Autoimmune"}
    KMT2D -->|"therapeutic target"| Autoimmune
    Lymphoma{"Lymphoma"}
    KMT2D -->|"expressed in"| Lymphoma
    Als{"Als"}
    KMT2D -->|"expressed in"| Als
    Cancer{"Cancer"}
    KMT2D -->|"expressed in"| Cancer
    Tumor{"Tumor"}
    KMT2D -->|"expressed in"| Tumor
    Jak_Stat(["Jak-Stat"])
    KMT2D -->|"therapeutic target"| Jak_Stat
    NF__B["NF-KappaB"]
    KMT2D -->|"expressed in"| NF__B
    STAT3["STAT3"]
    KMT2D -->|"expressed in"| STAT3
    DDX3X["DDX3X"]
    KMT2D -->|"expressed in"| DDX3X
    APOPTOSIS["APOPTOSIS"]
    KMT2D -->|"expressed in"| APOPTOSIS
    RB1["RB1"]
    KMT2D -->|"expressed in"| RB1
    TET2["TET2"]
    TET2 -->|"associated with"| KMT2D
    STAT3 -->|"therapeutic target"| KMT2D
    GAIN["GAIN"]
    GAIN -->|"therapeutic target"| KMT2D
    CDKN2A["CDKN2A"]
    CDKN2A -->|"expressed in"| KMT2D
    TP53["TP53"]
    TP53 -->|"expressed in"| KMT2D
    TET2 -->|"expressed in"| KMT2D
    MYD88["MYD88"]
    MYD88 -->|"expressed in"| KMT2D
    style KMT2D fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0