| Gene Symbol | LMX1A |
| Full Name | LIM Homeobox Transcription Factor 1 Alpha |
| Chromosome | 1q22 |
| Protein Type | Transcription Factor |
| Function | It regulates gene expression through binding to specific DNA sequences and recruiting transcriptional co-activators or co-repressors. |
| Primary Expression | substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) dopaminergic neurons |
| Pathways | WNT signaling, WNT |
| UniProt ID | Q8WWI6 |
| NCBI Gene ID | 26118 |
| Ensembl ID | ENSG00000187123 |
| GeneCards | LMX1A |
| Human Protein Atlas | LMX1A |
| Region | Expression Level |
| [Substantia nigra](/brain-regions/substantia-nigra) | High |
| Ventral tegmental area | High |
| Associated Diseases | neurodegeneration |
| Interactions | NURR1, PRKN, PARKIN, ASCL1, BDNF, NGF |
| KG Connections | 46 knowledge graph edges |
| Databases | GeneCardsHPASTRING |