gene 682 words KG: MAP1LC3C 2026-03-26
kind:genesection:genesstate:published
Contents

MAP1LC3C Gene

🧬 Gene Info
Gene SymbolMAP1LC3C
Full NameMicrotubule-Associated Protein 1 Light Chain 3 Gamma
Chromosome4q26
FunctionMAP1LC3C encodes one of the microtubule-associated proteins (MAP1) light chain 3 family, also known as LC3C
Primary Expressionvarious tissues with notable expression in: - Brain (cerebral cortex, hippocampus, [cerebellum]
UniProt ID[Q9GZU8](https://www.uniprot.org/uniprot/Q9GZU8) Category
Ensembl IDENSG00000143153
OMIM609459
GeneCardsMAP1LC3C
Human Protein AtlasMAP1LC3C
Associated DiseasesCancer, Lung Cancer
KG Connections13 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

SASP-Mediated Complement Cascade Amplification
Score: 0.70
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (4)

Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (8)

Proposed experiment from debate on Synaptic pruning by micro
falsification · proposed · Score: 0.40
Proposed experiment from debate on Senolytics targeting p16/
falsification · proposed · Score: 0.40
Mechanism: Why Does Amyloid Removal Only Slow Decline 27%?
clinical · proposed · Score: 0.40
Experiment: Autoimmune Hypothesis Testing in AD
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40

See Also (6)

NDUFV2 Gene
gene · KG edge: associated_with
MAP1LC3B — LC3B
gene · KG edge: associated_with
MAP1LC3A Gene
gene · KG edge: associated_with
ATG14 Gene
gene · KG edge: associated_with
Autophagy Enhancement Drug Screening for Neurodegenerat
experiment · KG edge: associated_with

Knowledge Graph (12 edges)

MAP1LC3C associated_with ATG14
MAP1LC3C associated_with NDUFV2
MAP1LC3C associated_with MAP1LC3A
MAP1LC3C associated_with MAP1LC3B
MAP1LC3C associated_with ROS
MAP1LC3C associated_with CANCER
MAP1LC3C associated_with LC3B
MAP1LC3C associated_with NADH
MAP1LC3C associated_with AUTOPHAGY
MAP1LC3C associated_with Cancer