gene 2,091 words KG: NLGN3 2026-03-29
section:geneskind:genetopic:alzheimerstopic:parkinsonstopic:autism
Contents

NLGN3 Gene

🧬 Gene Info
Gene SymbolNLGN3
Full NameNeuroligin 3
ChromosomeXq13.1
Functionencodes a postsynaptic cell adhesion molecule that is essential for the formation, function, and plasticity of synapses throughout the mammalian brain.
Primary Expressionneurons throughout the brain, with particularly high levels in the cerebral cortex, hippocampus, and basal ganglia
Molecular Weight~165 kDa
Amino Acids461 aa
Exons19
PathwaysMtor, Neuroprotection, PI3K-mTOR, PI3K-mTOR pathway
UniProt IDQ9NZU4
NCBI Gene ID54413
Ensembl IDENSG00000174373
OMIM300336
GeneCardsNLGN3
Human Protein AtlasNLGN3
Associated DiseasesALS, high-grade gliomas
InteractionsADAM10, Rb, BRAIN INJURY, S6K1, AND, NEURON
KG Connections57 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph