| Gene Symbol | NOTCH2NLC |
| Full Name | Notch 2 N-terminal-like protein |
| Chromosome | 1q12 |
| Protein Type | Receptor |
| Function | In the normal nervous system, Notch signaling regulates critical processes |
| Pathways | NOTCH, Notch, Notch signaling, Notch pathway |
| UniProt ID | Q9P0M4 |
| NCBI Gene ID | 100302521 |
| Ensembl ID | ENSG00000237289 |
| GeneCards | NOTCH2NLC |
| Human Protein Atlas | NOTCH2NLC |
| N-terminal signal peptide | Directs protein trafficking to the cell membrane |
| Notch repeat (NR) domain | Specific to Notch-like proteins |
| Transmembrane domain | Spans the cell membrane |
| C-terminal intracellular domain | Contains transcriptional activation domains (although NOTCH2NLC is considered a pseudogene that may not produce a functional protein) |
| Associated Diseases | Essential Tremor, frontotemporal dementia, neurodegeneration, neuronal hyperexcitability, Neuronal Intranuclear Inclusion Disease |
| Interactions | AND, AUTOPHAGY, G3BP1, GENES, INFLAMMATION, NEURODEGENERATIVE DISEASES |
| KG Connections | 40 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
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