gene 1,055 words KG: ENO1
Contents

ENO1 Gene

🧬 Gene Info
Gene SymbolENO1
Full NameEnolase 1 (Alpha-enolase)
Chromosome1p36.23
Functionencodes a 433-amino acid protein (approximately 47 kDa).
Subcellular Localizationthe cell surface
Molecular Weight47 kDa
Amino Acids433 aa
PathwaysApoptosis, Autophagy, Glycolysis, Immune Response, Inflammasome
UniProt IDP06733
NCBI Gene ID2023
Ensembl IDENSG00000169064
OMIM172430
GeneCardsENO1
Human Protein AtlasENO1
Associated DiseasesAging, Cancer, Carcinoma, Ms, Parkinson, Tumor
InteractionsHSPA1A, FLT1, HSPA8, GAPDH, PDK3, HK2
KG Connections156 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (8)

Chaperone-Mediated APOE4 Refolding Enhancement
Score: 0.48
Microbial Metabolite-Mediated α-Synuclein Disaggregation
Score: 0.45
Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam
Score: 0.62
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Proteostasis Enhancement via APOE Chaperone Targeting
Score: 0.50

Related Analyses (2)

Synaptic pruning by microglia in early AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (12)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: regulates
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: activates
E2F1 Gene
gene · KG edge: activates
CREB1 Gene
gene · KG edge: activates

Knowledge Graph (12 edges)

ENO1 associated_with DDX5
ENO1 associated_with CD8
ENO1 associated_with ATM
ENO1 biomarker_for DNAJA1
ENO1 interacts_with HSPA1A
ENO1 interacts_with FLT1
ENO1 interacts_with HSPA8
ENO1 biomarker_for GPX4
ENO1 biomarker_for MAP2K1
ENO1 biomarker_for VCAM1