gene 2,128 words KG: PRKCI 2026-03-24
kind:genesection:genesstate:published
Contents

PRKCI

🧬 Gene Info
Gene SymbolPRKCI
Chromosome3q26.2
Protein TypeKinase
Functionencodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases.
Subcellular LocalizationPRKCI localizes to multiple cellular compartments:
PathwaysOxidative Stress, Apoptosis, Akt, Ferroptosis, Dna Methylation
Ensembl IDENSG00000163558
GeneCardsPRKCI
Human Protein AtlasPRKCI
Associated Diseasesneurodegeneration
InteractionsAKT, ALZHEIMER, NEURON, ALZHEIMER'S DISEASE, AND
KG Connections24 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.66
APOE-Dependent Autophagy Restoration
Score: 0.61
Extracellular Matrix Stiffness Modulation
Score: 0.43
Piezoelectric Nanochannel BBB Disruption
Score: 0.41
Quantum Coherence Disruption in Cellular Communication
Score: 0.34

Related Analyses (2)

Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived

See Also (12)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: therapeutic_target
Alzheimer Indonesia
institution · KG edge: activates
APP Gene Dosage Reduction Therapy for Down Syndrome
idea · KG edge: therapeutic_target
VDAC1 — Voltage Dependent Anion Channel 1
gene · KG edge: therapeutic_target
IL16 Gene
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

PRKCI activates AKT
PRKCI therapeutic_target VDAC1
PRKCI therapeutic_target IL16
PRKCI activates ALZHEIMER
PRKCI therapeutic_target AMYLOID
PRKCI therapeutic_target FERROPTOSIS
PRKCI activates NEURON
PRKCI activates Alzheimer
PRKCI therapeutic_target Oxidative Stress
PRKCI therapeutic_target Apoptosis