gene 861 words KG: RAB11A 2026-03-22
kind:genesection:genesstate:published
Contents

RAB11A — Ras-Related Protein Rab-11A

🧬 Gene Info
Gene SymbolRAB11A
Full NameRas-Related Protein Rab-11A
AliasesPage for RAB11A
FunctionRAB11A functions in the recycling endosome compartment
Molecular Weight24 kDa
Amino Acids216 aa
UniProt IDRAB11A
Ensembl IDENSG00000103740
GeneCardsRAB11A
Human Protein AtlasRAB11A
Receptor recyclingControls recycling of AMPA, NMDA, and GABA receptors to the plasma membrane<sup>[1]</sup>
Synaptic plasticityEssential for activity-dependent synaptic modification
Neurotrophin traffickingRegulates BDNF/TrkB receptor recycling
Membrane protein turnoverParticipates in cargo sorting in the recycling pathway
Cell divisionRegulates cell polarity and cytokinesis (non-neuronal)
Associated Diseasesneurodegeneration
KG Connections12 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (5)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Circadian-Synchronized Proteostasis Enhancement
Score: 0.58
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.41

Related Analyses (7)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

See Also (10)

Ubiquitin
protein · KG edge: regulates
Packard Center for ALS Research
institution · KG edge: regulates
VAMP7 Gene
gene · KG edge: regulates
RAB8A — RAB8A, Member RAS Oncogene Family
gene · KG edge: regulates
RAB27A Gene
gene · KG edge: regulates

Knowledge Graph (12 edges)

RAB11A regulates DNAJC5
RAB11A regulates ATG7
RAB11A regulates VAMP7
RAB11A regulates UBIQUITIN
RAB11A regulates RAB27A
RAB11A regulates AND
RAB11A regulates Ms
RAB11A regulates Als
RAB11A regulates Amyotrophic Lateral Sclerosis
RAB8A regulates RAB11A