| Gene Symbol | SALL1 |
| Aliases | Sal-like protein 1 |
| Chromosome | 16q12.1 |
| Protein Type | Transcription Factor |
| Function | is a zinc-finger transcription factor that plays critical roles in embryonic development and cellular differentiation. |
| Primary Expression | all microglial subpopulations
- Maintained in adult microglia throughout life
- Not expressed in neurons, astrocytes, or oligodendrocytes
- Specific t |
| Amino Acids | 322 aa |
| Exons | Multiple exons encoding the full-length protein |
| GeneCards | SALL1 |
| Human Protein Atlas | SALL1 |
| Gene | Tissue Expression |
| SALL1 | Brain (microglia), kidney, ear |
| SALL2 | Ubiquitous |
| SALL3 | Brain, other tissues |
| SALL4 | Stem cells |
| Associated Diseases | Alzheimer's disease pathogenesis: |
| Interactions | TMEM119, TREM2, HEXB, APOE, CX3CR1, P2RY12 |
| KG Connections | 25 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |