| Gene Symbol | SPG21 |
| Full Name | Spastic Paraplegia 21 (Maspardin) |
| Aliases | SPG21/Mast syndrome |
| Chromosome | 15q22.31 |
| Protein Family | Alpha/beta hydrolase fold family |
| Protein Type | Hydrolase |
| Function | is a gene that encodes a crucial protein involved in endosomal trafficking, autophagy, and synaptic vesicle dynamics. |
| Molecular Weight | 35 kDa |
| Amino Acids | 311 aa |
| Exons | 11 |
| Pathways | Mtor |
| UniProt ID | [Q9BRK0](https://www.uniprot.org/uniprot/Q9BRK0) |
| Ensembl ID | ENSG00000046753 |
| GeneCards | SPG21 |
| Human Protein Atlas | SPG21 |
| Associated Diseases | neurodegeneration |
| Interactions | FYCO1, TFEB, RAB7A, MTORC1, MTOR, ENDOSOMES |
| KG Connections | 15 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |