gene 1,428 words KG: STAT5A 2026-03-27
kind:genesection:genesstate:published
Contents

STAT5A Gene

🧬 Gene Info
Gene SymbolSTAT5A
Full NameSignal Transducer and Activator of Transcription 5A
Chromosome12q13
Functionis a member of the STAT (Signal Transducer and Activator of Transcription) family of transcription factors.
Primary Expressionneurons and glia, where it serves important functions: [@stat5a_neurons_2016]
Molecular Weight~90 kDa
Amino Acids793 aa
Exons19
PathwaysJAK-STAT pathway
UniProt IDP42229
NCBI Gene ID6776
Ensembl IDENSG00000168661
OMIM601711
GeneCardsSTAT5A
Human Protein AtlasSTAT5A
Associated Diseasesneurodegeneration
InteractionsDLAT
KG Connections21 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (6)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
APOE-Dependent Autophagy Restoration
Score: 0.61
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
Ocular Immune Privilege Extension
Score: 0.47
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45

Related Analyses (6)

Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Mechanistic role of APOE in neurodegeneration
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived

See Also (15)

Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: expressed_in
Packard Center for ALS Research
institution · KG edge: expressed_in
STAT6 — Signal Transducer and Activator of Transcriptio
gene · KG edge: associated_with
STAT4 Gene
gene · KG edge: associated_with
STAT2 Gene - Signal Transducer and Activator of Transcr
gene · KG edge: associated_with

Knowledge Graph (12 edges)

STAT5A expressed_in APOPTOSIS
STAT5A regulates BCL-2
STAT5A expressed_in Als
STAT5A expressed_in Apoptosis
STAT5A contributes_to IFN
STAT5A contributes_to Jak-Stat
DLAT activates STAT5A
JAK1 associated_with STAT5A
STAT6 associated_with STAT5A
JAK2 associated_with STAT5A