| Gene Symbol | JAK1 |
| Full Name | Janus Kinase 1 |
| Chromosome | 1p31.3 |
| Function | JAK1 encodes Janus kinase 1, a non-receptor tyrosine kinase that mediates signaling for type I and type II cytokine receptors. |
| Primary Expression | most cell types |
| Pathways | JAK-STAT pathway |
| UniProt ID | [P23458](https://www.uniprot.org/uniprot/P23458) |
| Ensembl ID | ENSG00000162433 |
| OMIM | 147795 |
| GeneCards | JAK1 |
| Human Protein Atlas | JAK1 |
| Associated Diseases | Alzheimer, Alzheimer'S Disease, Huntington, Huntington's disease, Tumor |
| Known Drugs/Compounds | quercetin, Ponicidin |
| Interactions | IL6, HIF1A, STAT1, CXCL10, STING, TNF |
| KG Connections | 359 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |