gene 1,293 words KG: SYNA
Contents

SYNA — Synapsin I

🧬 Gene Info
Gene SymbolSYNA
Full NameSynapsin I
Chromosome17q21.31
Functionis a neuronal phosphoprotein associated with the cytoplasmic surface of synaptic vesicles.
Primary ExpressionBrain (cortex, hippocampus, cerebellum), neurons
Subcellular Localizationpresynaptic terminals where it associates with the cytoplasmic surface of synaptic vesicles. [@takamori2006]
Amino Acids706 aa
UniProt IDP17600
NCBI Gene ID6853
Ensembl IDENSG00000135547
OMIM313440
GeneCardsSYNA
Human Protein AtlasSYNA
Synapsin Ia706 amino acids
Synapsin Ib669 amino acids (lacking domain E)
KG Connections19 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (177)

Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.67
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
Metabolic Reprogramming via Microglial Glycolysis Inhibition
Score: 0.67
Partial Neuronal Reprogramming via Modified Yamanaka Cocktai
Score: 0.67
Enhancing Vagal Cholinergic Signaling to Restore Gut-Brain A
Score: 0.67
Astrocyte MCT1/MCT4 Ratio Disruption with Metabolic Uncoupli
Score: 0.67
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.67
Mitochondrial-Lysosomal Contact Site Engineering
Score: 0.67
Lipid Droplet Dynamics as Phenotype Switches
Score: 0.67
GAP43-mediated tunneling nanotube stabilization enhances neu
Score: 0.67
Complement C1q Subtype Switching
Score: 0.66
Biorhythmic Interference via Controlled Sleep Oscillations
Score: 0.66
Temporal TET2-Mediated Hydroxymethylation Cycling
Score: 0.66
Mitochondrial RNA Granule Rescue Pathway
Score: 0.66
Optogenetic Microglial Deactivation via Engineered Inhibitor
Score: 0.66
Arginine Methylation Enhancement Therapy
Score: 0.65
KDM6A-Mediated H3K27me3 Rejuvenation
Score: 0.65
Nucleolar Stress Response Normalization
Score: 0.65
The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction
Score: 0.65
Mitochondrial Calcium Buffering Enhancement via MCU Modulati
Score: 0.65
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Related Analyses (30)

Synaptic pruning by microglia in early AD
neurodegeneration · completed
Extracellular vesicle biomarkers for early AD detection
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (14)

Microglia
cell · KG edge: co_discussed
Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: co_discussed
Neurodegeneration
disease · KG edge: implicated_in
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: co_discussed
Microglia in Neurodegeneration
entity · KG edge: co_discussed

Knowledge Graph (12 edges)

TFEB binds_to SYNA
SYNA co_discussed SPP1
SYNA co_discussed DYSF
GNAL co_discussed SYNA
SYNA co_discussed C1QA
SYNA co_discussed GRN
SYNA co_discussed CTSB
COMPLEMENT CASCADE co_discussed SYNA
C1Q co_discussed SYNA
MICROGLIA co_discussed SYNA

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