gene 1,293 words KG: SYNA
Contents

SYNA — Synapsin I

🧬 Gene Info
Gene SymbolSYNA
Full NameSynapsin I
Chromosome17q21.31
Functionis a neuronal phosphoprotein associated with the cytoplasmic surface of synaptic vesicles.
Primary ExpressionBrain (cortex, hippocampus, cerebellum), neurons
Subcellular Localizationpresynaptic terminals where it associates with the cytoplasmic surface of synaptic vesicles. [@takamori2006]
Amino Acids706 aa
UniProt IDP17600
NCBI Gene ID6853
Ensembl IDENSG00000135547
OMIM313440
GeneCardsSYNA
Human Protein AtlasSYNA
Synapsin Ia706 amino acids
Synapsin Ib669 amino acids (lacking domain E)
KG Connections19 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (177)

Glial Glycocalyx Remodeling Therapy
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Grid Cell-Specific Metabolic Reprogramming via IDH2 Enhancem
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Synthetic Biology Rewiring via Orthogonal Receptors
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Ephrin-B2/EphB4 Axis Manipulation
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Targeting Bacterial Curli Fibrils to Prevent α-Synuclein Cro
Score: 0.64
Glycine-Rich Domain Competitive Inhibition
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Transglutaminase-2 Cross-Linking Inhibition Strategy
Score: 0.64
FOXO3-Longevity Pathway Epigenetic Reprogramming
Score: 0.63
Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.63
Quantum Coherence Disruption in Cellular Communication
Score: 0.63
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.62
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.62
TFEB-PGC1α Mitochondrial-Lysosomal Decoupling
Score: 0.62
Cholesterol-CRISPR Convergence Therapy for Neurodegeneration
Score: 0.62
Pharmacological Enhancement of APOE4 Glycosylation
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Related Analyses (30)

Synaptic pruning by microglia in early AD
neurodegeneration · completed
Extracellular vesicle biomarkers for early AD detection
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

See Also (14)

Microglia
cell · KG edge: co_discussed
Neuroinflammation PET Imaging in CBS/PSP
diagnostic · KG edge: co_discussed
Neurodegeneration
disease · KG edge: implicated_in
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: co_discussed
Microglia in Neurodegeneration
entity · KG edge: co_discussed

Knowledge Graph (12 edges)

TFEB binds_to SYNA
SYNA co_discussed SPP1
SYNA co_discussed DYSF
GNAL co_discussed SYNA
SYNA co_discussed C1QA
SYNA co_discussed GRN
SYNA co_discussed CTSB
COMPLEMENT CASCADE co_discussed SYNA
C1Q co_discussed SYNA
MICROGLIA co_discussed SYNA

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