| Gene Symbol | Secreted Phosphoprotein 1 (Osteopontin) |
| Chromosome | 4q21.1 |
| Function | encodes a secreted matricellular glycoprotein that functions as a cytokine, chemokine, and extracellular matrix protein. |
| Amino Acids | 314 aa |
| Pathways | Amyloid, Angiogenesis, Apoptosis, Complement, Immune Response |
| UniProt ID | P08421 |
| NCBI Gene ID | 6696 |
| Ensembl ID | ENSG00000118733 |
| OMIM | 166490 |
| Associated Diseases | AD, Als, Alzheimer, Alzheimer's disease, CCLM, Cancer |
| Known Drugs/Compounds | ursolic acid, amyloid-beta oligomers, BaP, Bap, rapamycin |
| Interactions | GRN, C1QA, CTSB, PTEN, GBM, STAT1 |
| SciDEX Hypotheses | Temporal SPP1 Inhibition During Critical Windows |
| KG Connections | 451 knowledge graph edges |
| Databases | GeneCardsHPASTRING |