gene 1,067 words KG: TERC 2026-03-21
kind:genesection:genesstate:published
Contents

TERC Gene

🧬 Gene Info
Gene SymbolTERC
Full NameTelomerase RNA Component
Chromosome3q26.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Amino Acids~451 nucleotides
PathwaysTelomere Dysfunction
NCBI Gene ID7012
Ensembl IDENSG00000264364
OMIM602322
GeneCardsTERC
Human Protein AtlasTERC
RNA TypeLong non-coding RNA (lncRNA)
Length~451 nucleotides
Associated DiseasesALS, Inflammation, Ms, Senescence
InteractionsMICRORNAS, IL-6, IL-8
KG Connections62 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (30)

Transcriptional Autophagy-Lysosome Coupling
Score: 0.66
ACSL4-Driven Ferroptotic Priming in Disease-Associated Micro
Score: 0.66
CYP46A1 Overexpression Gene Therapy
Score: 0.63
Multi-Modal Stress Response Harmonization
Score: 0.60
Selective APOE4 Degradation via Proteolysis Targeting Chimer
Score: 0.59

Related Analyses (29)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · failed
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (4)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: contributes_to
Packard Center for ALS Research
institution · KG edge: associated_with
Genes
index · KG edge: associated_with
Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: contributes_to

Knowledge Graph (12 edges)

TERC associated_with TERT
TERC contributes_to TERT
TERC involved_in Telomere Dysfunction
TERC regulates Telomere Dysfunction
TERC involved_in Telomere Maintenance
TERC causes Telomere Dysfunction
TERC regulates Senescence
TERC associated_with Als
TERC regulates Ms
TERC regulates Inflammation