gene 1,067 words KG: TERC
Contents

TERC Gene

🧬 Gene Info
Gene SymbolTERC
Full NameTelomerase RNA Component
Chromosome3q26.2
Functionis an important component in the neurobiology of neurodegenerative diseases.
Amino Acids~451 nucleotides
PathwaysTelomere Dysfunction
NCBI Gene ID7012
Ensembl IDENSG00000264364
OMIM602322
GeneCardsTERC
Human Protein AtlasTERC
Associated DiseasesAls, Inflammation, Ms, Senescence
InteractionsIL-6, IL-8, MICRORNAS
KG Connections60 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (76)

Metabolic Switch Targeting for A1→A2 Repolarization
Score: 0.73
TFAM overexpression creates mitochondrial donor-recipient gr
Score: 0.73
Sleep Spindle-Synaptic Plasticity Enhancement
Score: 0.72
Magnetosonic-Triggered Transferrin Receptor Clustering
Score: 0.72
Retinal Vascular Microcirculation Rescue
Score: 0.72
Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides
Score: 0.72
HDAC3-Selective Inhibition for Clock Reset
Score: 0.71
Autophagosome Maturation Checkpoint Control
Score: 0.71
Axonal RNA Transport Reconstitution
Score: 0.70
Mitochondrial Transfer Pathway Enhancement
Score: 0.70
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69
Palmitoylation-Targeted BACE1 Trafficking Disruptors
Score: 0.69
Extracellular Matrix Stiffness Modulation
Score: 0.69
Ganglioside Rebalancing Therapy
Score: 0.69
Cross-Seeding Prevention Strategy
Score: 0.69
Pericyte Contractility Reset via Selective PDGFR-β Agonism
Score: 0.68
Flotillin-1 Stabilization Compounds
Score: 0.68
R-Loop Resolution Enhancement Therapy
Score: 0.68
Astrocytic Connexin-43 Upregulation Enhances Neuroprotective
Score: 0.68
RAB27A-dependent extracellular vesicle engineering for mitoc
Score: 0.67
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Related Analyses (28)

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Microglia-astrocyte crosstalk amplification loops in neurode
neurodegeneration · archived
Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (4)

Epigenetic Clocks in Neurodegeneration — Causal Drivers
experiment · KG edge: contributes_to
Genes
index · KG edge: associated_with
Packard Center for ALS Research
institution · KG edge: associated_with
Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: contributes_to

Knowledge Graph (12 edges)

TERT associated_with TERC
TERT expressed_in TERC
TERC involved_in Telomere Dysfunction
TERC regulates Telomere Dysfunction
TERC involved_in Telomere Maintenance
TERT encodes TERC
TERC causes Telomere Dysfunction
TERC regulates Senescence
TERC associated_with Als
TERC regulates Ms

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