gene 757 words KG: TRKC
Contents

TRKC Gene

🧬 Gene Info
Gene SymbolTRKC
Chromosome15q25.3
Protein TypeReceptor
FunctionTrkC is the primary receptor for neurotrophin-3 (NT-3)
Primary Expressionproprioceptive neurons, motor neurons, and certain populations of hippocampal and cortical neurons
Molecular Weight145 kDa
Amino Acids821 aa
Exons26
Pathwayssignaling: - Supports sensory neuron survival, PI3K, MAPK
GeneCardsTRKC
Human Protein AtlasTRKC
Associated DiseasesAlzheimer
InteractionsALZHEIMER, AMYLOID, Amyloid Beta, Aβ, Bdnf, BDNF
KG Connections69 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (3)

Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.82
CYP46A1 Overexpression Gene Therapy
Score: 0.77
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.69

Related Analyses (3)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

See Also (13)

Myelin Basic Protein (MBP) - Biomarker
biomarker · KG edge: transports
blarcamesine-axon
clinical_trial · KG edge: transports
NeuRon Therapeutics
company · KG edge: activates
Apoptosis in Neurodegeneration
entity · KG edge: associated_with
Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: activates

Knowledge Graph (12 edges)

APP regulates TRKC
TRKC regulates TRKB
NGF interacts_with TRKC
NTRK2 associated_with TRKC
BDNF interacts_with TRKC
TRKC interacts_with TRKB
TRKB regulates TRKC
late activates TRKC
TRKB activates TRKC
late regulates TRKC

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