| Gene Symbol | TRKB |
| Chromosome | 9q21.33 |
| Protein Type | Receptor |
| Function | is a high-affinity receptor tyrosine kinase that serves as the primary signaling receptor for brain-derived neurotrophic factor (BDNF) and neurotrophin-4 (NT-4). |
| Subcellular Localization | </th><td>Cell membrane, endosomes, nucleus, mitochondria</td></tr> |
| Molecular Weight | 140 kDa |
| Amino Acids | 796 aa |
| Exons | 24 |
| Pathways | Akt, Apoptosis, Cell Cycle, Long-Term Potentiation, Mapk |
| UniProt ID | Q16620 |
| NCBI Gene ID | 4915 |
| Ensembl ID | ENSG00000148053 |
| GeneCards | TRKB |
| Human Protein Atlas | TRKB |
| Associated Diseases | ALS, Aging, Alzheimer, Alzheimer'S Disease, Cancer |
| Interactions | MMP2, SYN3, MMP9, BDNF, PI3K, MTOR |
| KG Connections | 973 knowledge graph edges |
| Databases | GeneCardsHPASTRING |