| Gene Symbol | HDAC10 |
| Aliases | Histone Deacetylase 10 |
| Chromosome | 22q13.33. |
| Protein Type | Gene |
| Function | is a class IIb histone deacetylase encoded by the HDAC10 gene located on chromosome 22q13. |
| Primary Expression | both neurons and glia, with astrocytic and microglial expression particularly relevant to understanding its role in neuroinflammation |
| Subcellular Localization | and function |
| Molecular Weight | 78 kDa |
| Amino Acids | 669 aa |
| Exons | 16 |
| Pathways | Epigenetic |
| GeneCards | HDAC10 |
| Human Protein Atlas | HDAC10 |
| N-terminal catalytic domain (aa 1-370) | Contains the active site residues required for histone deacetylase activity |
| Nuclear export signal (NES) | Located at residues 85-95, mediating cytoplasmic localization |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Interactions | AND, DNMT3A, HDAC1 |
| KG Connections | 15 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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