gene 1,035 words KG: VEGF 2026-03-24
kind:genesection:genesstate:published
Contents

VEGF (Vascular Endothelial Growth Factor)

🧬 Gene Info
Gene SymbolVEGF
AliasesVascular Endothelial Growth Factor
FunctionVEGF serves multiple physiological functions
Primary Expressionhippocampus, motor cortex, cerebellum, cortex, striatum
PathwaysAkt, Amyloid, Apoptosis, Complement, Epigenetic
UniProt ID[P15692](https://www.uniprot.org/uniprot/P15692)
NCBI Gene ID7422
GeneCardsVEGF
Human Protein AtlasVEGF
Associated DiseasesALS, Aging, Alzheimer, Alzheimer'S Disease
Known Drugs/CompoundsRAPAMYCIN, bevacizumab, levodopa, LEVODOPA, QUERCETIN, rapamycin
InteractionsFGF2, ANGPT1, PDGFRB, VEGFB, BMP2, STAT3
KG Connections1347 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (30)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
SASP-Mediated Complement Cascade Amplification
Score: 0.70
Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna
Score: 0.68
Nutrient-Sensing Epigenetic Circuit Reactivation
Score: 0.67
Transcriptional Autophagy-Lysosome Coupling
Score: 0.66

Related Analyses (14)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Digital biomarkers and AI-driven early detection of neurodeg
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (4)

Irisin treatment in mouse femur fracture healing model
validation · proposed · Score: 0.90
Cytochrome Therapeutics
clinical · proposed · Score: 0.40
Neural Stem Cell Therapy for Alzheimer's Disease
clinical · proposed · Score: 0.40
Vascular Contribution to Alzheimer's Disease — Beyond Amyloi
validation · proposed · Score: 0.40

See Also (4)

Aging vs Neurodegeneration: Mechanistic Comparison Matr
mechanism · KG edge: activates
Alzheimer Indonesia
institution · KG edge: activates
AKT1 Gene
gene · KG edge: interacts_with
ABCG2 (BCRP) - ATP Binding Cassette Subfamily G Member
gene · KG edge: therapeutic_target

Knowledge Graph (12 edges)

VEGF contributes_to POEMS_SYNDROME
VEGF activates FGF2
VEGF activates ANGPT1
VEGF activates PDGFRB
VEGF activates VEGFB
VEGF expressed_in TNF
VEGF associated_with BAX
VEGF associated_with FIS1
VEGF associated_with TRAF6
VEGF associated_with CHOP