Contents

SHH — Sonic Hedgehog

🧬 Gene Info

Gene Symbol	SHH
Full Name	Sonic Hedgehog
Chromosome	7q36.3
Function	is a pivotal signaling molecule that plays fundamental roles in embryonic development, tissue patterning, and adult tissue homeostasis.
Primary Expression	Substantia nigra, Cerebellum, Cortex, Hippocampus, Developing brain, Adult neural stem cells
Molecular Weight	19 kDa
Amino Acids	462 aa
Pathways	Differentiation, Hedgehog, Sonic Hedgehog, Wnt
UniProt ID	Q15465
NCBI Gene ID	6469
Ensembl ID	ENSG00000164690
OMIM	600725
GeneCards	SHH
Human Protein Atlas	SHH
Associated Diseases	Aging, ALS, Alzheimer, Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Cancer
Interactions	ADCY3, AKT, ASTROCYTE, ASTROCYTES, ATXN3, CANCER
KG Connections	228 knowledge graph edges
Databases	GeneCards HPA STRING

Knowledge Graph