gene

adcy3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about adcy3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections
0Hypotheses
0Analyses
11Outgoing
5Incoming

No summary available yet. View on Wiki →

🧬 Gene Info
Gene SymbolADCY3
Full NameAdenylate cyclase 3
Chromosome2p23.3
Protein TypeEnzyme
Functionis a member of the adenylate cyclase family of enzymes that catalyze the conversion of ATP to cyclic AMP (cAMP), a ubiquitous second messenger critical for cellular signaling.
Primary Expressionolfactory sensory neurons where it plays a critical role in odor detection and signal transduction
Molecular Weight140 kDa
Amino Acids244 aa
UniProt ID[O60236](https://www.uniprot.org/uniprot/O60236)
Ensembl IDENSG00000138031
OMIM600019
GeneCardsADCY3
Human Protein AtlasADCY3
Associated Diseasesobesity, Alzheimer's Disease
DatabasesGeneCardsNCBI GeneHPASTRING

Wiki Pages (9)

Knowledge base pages for this entity

ADCY3 — Adenylate Cyclase 3

gene · 2825 words

gnas-protein

protein · 2567 words

ADCY7 — Adenylate Cyclase 7

gene · 1992 words

OGT — O-GlcNAc Transferase

gene · 1429 words

ADCY2 — Adenylate Cyclase 2

gene · 1396 words

Pathway Diagram

flowchart TD
    N0["ADCY3"]
    N1["Als"]
    N0 -->|"activates"| N1
    N2["Ms"]
    N0 -->|"activates"| N2
    N3["Hedgehog"]
    N0 -->|"activates"| N3
    N4["HDAC6"]
    N0 -->|"activates"| N4
    N5["SHH"]
    N0 -->|"activates"| N5
    N6["GFRAL"]
    N0 -->|"activates"| N6
    N7["GDNF"]
    N0 -->|"activates"| N7
    N8["HEDGEHOG"]
    N0 -->|"activates"| N8
    N4 -->|"activates"| N0
    N7 -->|"activates"| N0
    N5 -->|"activates"| N0
    N6 -->|"activates"| N0
    N9["neurodegeneration"]
    N0 -->|"implicated in"| N9

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef therapeutic fill:#1a2a2a,stroke:#26a69a,color:#e0e0e0
    class N1 disease
    class N2 disease
    class N3 pathway
    class N4 gene
    class N5 gene
    class N6 gene
    class N7 gene
    class N8 gene

Outgoing (11)

TargetRelationTypeStr
Alsactivatesdisease0.65
Msactivatesdisease0.65
HDAC6activatesgene0.60
SHHactivatesgene0.60
GFRALactivatesgene0.60

Incoming (5)

SourceRelationTypeStr
HDAC6activatesgene0.60
GDNFactivatesgene0.60
SHHactivatesgene0.60
GFRALactivatesgene0.60
benchmark_ot_ad_answer_key:ADCY3data_indataset_row0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found