gene 1,200 words KG: IL18BP
Contents

IL18BP Gene

🧬 Gene Info
Gene SymbolIL18BP
Full NameInterleukin 18 Binding Protein
Chromosome11p15
Functionis an important component in the neurobiology of neurodegenerative diseases.
Primary Expressionvarious tissues throughout the body, with distinct patterns in the brain:
Molecular Weight40 kDa
Amino Acids100 aa
PathwaysNF-κB, MAPK signaling
UniProt ID[O95298](https://www.uniprot.org/uniprot/O95298)
Ensembl IDENSG00000147421
GeneCardsIL18BP
Human Protein AtlasIL18BP
Immunoglobulin-like domainSingle V-type Ig domain (~100 amino acids)
Molecular weightApproximately 40 kDa
SecretionConstitutively secreted by various cell types
Associated Diseasesneurodegeneration
InteractionsBdnf, BDNF, CANCER, CRH, CRHR1, FKBP5
KG Connections59 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

IL18 associated_with IL18BP
RAMP1 associated_with IL18BP
FKBP5 inhibits IL18BP
CRH inhibits IL18BP
CRHR1 inhibits IL18BP
NR3C1 inhibits IL18BP
BDNF inhibits IL18BP
IL18BP associated_with CALCA
CALCA associated_with IL18BP
IL18BP inhibits BDNF

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