Contents

CALCA Gene

🧬 Gene Info

Gene Symbol	CALCA
Function	It acts as a neuropeptide transmitter in primary sensory neurons (Aδ and C fibers) and modulates pain signals at both peripheral and central terminals.
Amino Acids	32 aa
Exons	6
Ensembl ID	ENSG00000110680
GeneCards	CALCA
Human Protein Atlas	CALCA
Calcitonin	A 32-amino acid peptide hormone primarily involved in calcium homeostasis, secreted by thyroid C-cells
α-CGRP	The predominant neuropeptide form in the nervous system
Katacalcin	A shorter peptide with uncertain function
CLR/RAMP1 receptor	The canonical CGRP receptor
CLR/RAMP2 or RAMP3 receptors	Associated with AM (adrenomedullin) receptors
Associated Diseases	neurodegeneration
Interactions	BDNF, CRH, CRHR1, FKBP5, IL18, NR3C1
KG Connections	33 knowledge graph edges
Databases	GeneCards UniProt NCBI Gene HPA STRING

Knowledge Graph