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mechanism 1,441 words KG: CREB
Contents

CREB-Independent Neuronal Survival Pathways in Neurodegeneration

⚙ Mechanism Info
NameCREB
Key Genes/ProteinsABETA, ACAT1, ACETYL-COA, ACHE, ACOX1, Actin
Related DiseasesAging
Linked Hypotheses15 hypotheses

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Related Hypotheses (28)

Gamma Oscillation Entrainment Enhances lncRNA-9969-Mediated
Score: 0.87CREB-Dependent Differential Complement Regulator Positioning
Score: 0.83Gamma entrainment induces activity-dependent BDNF release to
Score: 0.77Gamma entrainment corrects AD-related clock gene dysregulati
Score: 0.68LPS-primed microglial trained immunity establishes persisten
Score: 0.67Activity-Dependent Synaptic Tagging via CREB-BDNF-TrkB Signa
Score: 0.65Epigenetic Memory Reprogramming for Alzheimer's Disease
Score: 0.61Gamma-Entrained PV Interneuron Networks Enable Precision p-t
Score: 0.55Gamma-Entrained PV Interneurons Enable p-tau217-Guided Preci
Score: 0.555-HT2A/C Silencing Enables Sustained BDNF-TrkB Signaling for
Score: 0.55Alpha-Beta Oscillation Coupling Enhances lncRNA-9969-Mediate
Score: 0.46ADCY8-PKA-CREB Spatial Memory Enhancement
Score: 0.46Developmental Critical Period Extension for Memory Recovery
Score: 0.46Epigenetic Memory Engram Therapy for Alzheimer's Disease
Score: 0.46Alpha-Beta Oscillation Entrainment Enhances lncRNA-9969-Medi
Score: 0.43Theta-Gamma Coupling Modulates lncRNA-9969-Mediated Mitochon
Score: 0.42Alpha-Theta Oscillation Modulation Enhances lncRNA-9969-Medi
Score: 0.42cAMP/PKA-Dependent Transcription Factor Activation via Nutri
Score: 0.42Activity-Dependent Synaptic Tagging via CREB-IGF1-IGF1R Sign
Score: 0.38CREB-Mediated Differential CD55/CD46 Expression Creates Acti
Score: 0.38
pg 1/2Next →

Knowledge Graph (12 edges)

ALS associated_with CREB
CREB associated_with frontotemporal dementia
CREB associated_with NLRP3
CREB interacts_with PI3K
CREB interacts_with PKA
CREB interacts_with ERK
CREB regulates BDNF
cAMP activates CREB
CREB regulates BDNF_GENE
CREB activates BDNF_MRNA

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