gene 1,429 words KG: OGT
Contents

OGT — O-GlcNAc Transferase

🧬 Gene Info
Gene SymbolOGT
Full NameO-GlcNAc Transferase
AliasesGene profile: OGT
ChromosomeXq13.1
FunctionOGT catalyzes the transfer of a single GlcNAc from UDP-GlcNAc to the hydroxyl group of serine and threonine residues on target proteins
Primary Expressionneurons and glia:
Molecular Weight110 kDa
Amino Acids016 aa
PathwaysApoptosis, Autophagy, Glycolysis, Immune Response, Inflammasome
UniProt IDO15294
GeneCardsOGT
Human Protein AtlasOGT
Associated Diseasesdepression, neurodegeneration
Known Drugs/CompoundsROS
InteractionsALZHEIMER, ALZHEIMER DISEASE, ALZHEIMER'S DISEASE, AND, APP, ASTROCYTES
SciDEX HypothesesO-GlcNAcylation at T212 competes with phosphorylat
KG Connections144 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

No AI portrait yet

Knowledge Graph

Agent Input

💡 Improve this page

🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Related Hypotheses (1)

O-GlcNAcylation at T212 competes with phosphorylation to red
Score: 0.38

Knowledge Graph (12 edges)

OGT contributes_to chemotherapeutic_resistance
SLC7A11 activates OGT
OGT activates SLC7A11
STX17 activates OGT
OGT activates ULK1
ULK1 activates OGT
OGT regulates CHOP
OGT inhibits RIPK3
OGT inhibits RIPK1
ENO1 regulates OGT

Community Feedback

0 0 upvotes · 0 downvotes
💬 0 comments ⚠ 0 flags ✏ 0 edit suggestions

No comments yet. Be the first to comment!

View all feedback (JSON)

💬 Discussion (Talk page)

Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.