Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Platelets: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Cell Type | Platelets |
| Key Markers | VWF, AMYLOID, APP, AMYLOID-BETA, TAU, PCSK9 |
| Associated Diseases | Alzheimer's Disease, ALZHEIMER'S DISEASE, NEURODEGENERATION |
| Linked Hypotheses | 1 hypotheses |
Knowledge base pages for this entity
graph TD
Platelets["Platelets"] -->|"regulates"| Blood_Brain_Barrier_Maturation["Blood-Brain Barrier Maturation"]
style Blood_Brain_Barrier_Maturation fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Platelets["Platelets"] -->|"associated"| Angiogenesis["Angiogenesis"]
style Angiogenesis fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Platelets["Platelets"] -->|"contributes to"| Alzheimer_s_Disease["Alzheimer's Disease"]
style Alzheimer_s_Disease fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
Platelets["Platelets"] -->|"regulates"| Blood_Brain_Barrier["Blood-Brain Barrier"]
style Blood_Brain_Barrier fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
Platelets["Platelets"] -->|"associated"| AMYLOID["AMYLOID"]
style AMYLOID fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
Platelets["Platelets"] -->|"associated"| NEUROINFLAMMATION["NEUROINFLAMMATION"]
style NEUROINFLAMMATION fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Platelets["Platelets"] -->|"modulates"| Synaptic_Plasticity["Synaptic Plasticity"]
style Synaptic_Plasticity fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
VWF["VWF"] -->|"interacts"| Platelets["Platelets"]
style VWF fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
PCSK9["PCSK9"] -->|"activates"| Platelets["Platelets"]
style PCSK9 fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
style Platelets fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold| Target | Relation | Type | Str |
|---|---|---|---|
| Blood-Brain Barrier Maturation | regulates | process | 0.90 |
| Angiogenesis | associated_with | process | 0.90 |
| Alzheimer's Disease | contributes_to | disease | 0.90 |
| Angiogenesis | modulates | process | 0.90 |
| ALZHEIMER'S DISEASE | contributes_to | disease | 0.90 |
| AMYLOID | associated_with | protein | 0.90 |
| NEUROINFLAMMATION | associated_with | process | 0.90 |
| APP | expressed_in | protein | 0.90 |
| Synaptic Plasticity | modulates | process | 0.85 |
| AMYLOID-BETA | associated_with | protein | 0.85 |
| Tau Hyperphosphorylation | associated_with | process | 0.85 |
| Angiogenesis | activates | process | 0.85 |
| AMYLOID-BETA | modulates | protein | 0.85 |
| TAU | phosphorylates | protein | 0.85 |
| NEURODEGENERATION | contributes_to | disease | 0.85 |
| Synaptic Plasticity | regulates | process | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| VWF | interacts_with | protein | 0.95 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||