| Gene Symbol | ABCD2 |
| Full Name | ATP Binding Cassette Subfamily D Member 2 |
| Aliases | ABCD2PROTEIN |
| Chromosome | 12q12 |
| Protein Type | Transporter |
| Function | is a peroxisomal ATP-binding cassette transporter primarily involved in the import of very long-chain fatty acids (VLCFAs) and branched-chain fatty acids into peroxisomes for beta-oxidation[@berger... |
| Primary Expression | brain white matter, liver, and adrenal glands |
| Amino Acids | 706 aa |
| Ensembl ID | ENSG00000173208 |
| GeneCards | ABCD2 |
| Human Protein Atlas | ABCD2 |
| Two transmembrane domains (TMDs) | Six transmembrane helices that form the substrate translocation pore |
| Two nucleotide-binding domains (NBDs) | These bind and hydrolyze ATP to provide energy for transport |
| Brain | Neurons, astrocytes, and oligodendrocytes |
| Liver | Hepatocytes |
| Associated Diseases | Als, Ms |
| Interactions | ABCD1, ABCD3, BLOOD-BRAIN BARRIER DYSFUNCTION, CLDN5, CTNNB1, ICAM1 |
| KG Connections | 33 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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