| Gene Symbol | ADORA2B |
| Chromosome | 17p12 |
| Protein Type | Receptor |
| Function | encodes a G protein-coupled receptor that plays important roles in modulating cellular responses to adenosine. |
| Primary Expression | astrocytes, microglia, neurons, and endothelial cells of the [ |
| Subcellular Localization | </strong></td><td>Plasma membrane</td></tr> [@burnstock2016] |
| Molecular Weight | 44 kDa |
| Pathways | PI3K, MAPK Pathway, NF-κB Pathway, NF-κB |
| UniProt ID | P29274 |
| NCBI Gene ID | 136 |
| Ensembl ID | ENSG00000171490 |
| OMIM | 600446 |
| GeneCards | ADORA2B |
| Human Protein Atlas | ADORA2B |
| Associated Diseases | ALS, Inflammation |
| Known Drugs/Compounds | Caffeine |
| Interactions | P2RY12, P2RX1, P2RX4, P2RX7, P2RY1, P2RX5 |
| KG Connections | 55 knowledge graph edges |
| Databases | GeneCardsHPASTRING |