| Gene Symbol | APH1B |
| Full Name | Aph-1 Homolog B, Gamma-Secretase Subunit |
| Aliases | APH-1B |
| Chromosome | 15q22.2 |
| Function | Gamma-secretase complex subunit, cleaves APP and Notch |
| Subcellular Localization | </strong></td><td>Endoplasmic reticulum, Golgi apparatus, Plasma membrane</td></tr> |
| Molecular Weight | 28.5 kDa |
| Amino Acids | 257 |
| Pathways | Gamma-secretase complex, Notch signaling, APP processing |
| UniProt ID | Q8WW43 |
| NCBI Gene ID | 83464 |
| Ensembl ID | ENSG00000138613 |
| OMIM | 607630 |
| GeneCards | APH1B |
| Human Protein Atlas | APH1B |
| Associated Diseases | AD, AMI, Als, Alzheimer, Alzheimer's disease, RA |
| Interactions | APOE, IL6, SREBF1, PSEN2, A2M, DHCR24 |
| KG Connections | 101 knowledge graph edges |
| Databases | GeneCardsHPASTRING |