protein 599 words KG: ASCL1PROTEIN 2026-03-20
kind:proteinsection:proteinsstate:published
Contents

ASCL1 Protein

🔬 Protein Info
Gene SymbolASCL1
Full NameAchaete-Scute Homolog 1
Chromosome12p23.2
Protein FamilybHLH transcription factor family
Protein TypeTranscription Factor
Functionis a basic helix-loop-helix (bHLH) transcription factor essential for neural development, neurogenesis, and the differentiation of specific neuronal lineages.
Primary Expressionmultiple developmental contexts:
Subcellular LocalizationNucleus
Molecular Weight26.8 kDa
Amino Acids237 aa
UniProt IDP50567
NCBI Gene ID41
Ensembl IDENSG00000139352
OMIM100800
GeneCardsASCL1
Human Protein AtlasASCL1
Associated DiseasesCancer, Lung Cancer, Tumor
InteractionsBCL2, KDM6A, NEUROD1, GDNF, BDNF, LMX1A
KG Connections118 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph