| Gene Symbol | BCHEPROTEIN |
| Aliases | Pseudocholinesterase, Serum cholinesterase, BuChE, BChE |
| Protein Family | Cholinesterase family, Serpentine superfamily |
| Protein Type | Enzyme |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | the brain, particularly in glial cells, where it plays important roles in cholinergic signaling and has been implicated in neurodegenerative diseases |
| Subcellular Localization | Plasma, Liver, Brain (astrocytes, microglia) |
| Molecular Weight | ~68 kDa (tetrameric glycoprotein) |
| Amino Acids | 574 amino acids |
| GeneCards | BCHEPROTEIN |
| Human Protein Atlas | BCHEPROTEIN |
| Gene [@buche2013]
BCHE [@plasma2013]
[@buche2016]
UniProt | P06276 |
| PDB Structures | 1XUU, 2J4C, 4W2N |
| Length | 574 amino acids |
| Associated Diseases | Alzheimer, Alzheimer'S Disease, Anxiety, Dementia, Depression |
| Known Drugs/Compounds | antidementia drugs |
| Interactions | BACE1, CHRFAM7A, CNTN1, ESR1, GABRB3, MAPT |
| KG Connections | 156 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |