| Gene Symbol | BIP |
| Full Name | BiP - Binding Immunoglobulin (GRP78) |
| Aliases | HSPA5/GRP78 |
| Protein Type | Protein |
| Function | De Novo Folding: Binds nascent polypeptide chains as they enter the ER via the Sec61 translocon |
| Molecular Weight | 78 kDa |
| Amino Acids | 654 aa |
| Pathways | Autophagy, Mapk, Mtor, Pi3K/Akt, Unfolded Protein Response |
| UniProt ID | P11021 |
| GeneCards | BIP |
| Human Protein Atlas | BIP |
| Molecule | Interaction |
| [IRE1](/proteins/ire1) | Regulates activation |
| PERK | Regulates activation |
| ATF6 | Regulates activation |
| Associated Diseases | Tumor |
| Interactions | JNK1, JNK2, CHOP, JUN, P38, TSC2 |
| KG Connections | 181 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |