protein 1,171 words KG: GNAI3PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

GNAI3 (G Protein Alpha i3)

🔬 Protein Info
Gene SymbolGNAI3PROTEIN
Chromosome1p31.3.
Protein FamilyGαi/o/t family
Functionis a member of the Gαi family of heterotrimeric G proteins encoded by the GNAI3 gene on chromosome 1p31.
Primary ExpressionUbiquitous; highest in brain, heart, spleen
Subcellular LocalizationPlasma membrane, cytoplasm, Golgi apparatus
Molecular Weight40.4 kDa (354 amino acids)
Amino Acids354 aa
UniProt IDP08754
GeneCardsGNAI3PROTEIN
Human Protein AtlasGNAI3PROTEIN
GeneGNAI3
PDB1Y3A, 4G5O, 6CRK
Adenylyl cyclaseInhibition
GIRK channelsActivation
Associated DiseasesAls, Ms
InteractionsAKT, AKT1, GNB1, AMPD2, ATG5, MAVS
KG Connections57 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph