| Gene Symbol | GRM3 |
| Full Name | Glutamate Metabotropic Receptor 3 |
| Chromosome | 7q21.12 |
| Protein Family | Class C GPCR, mGluR family |
| Protein Type | Receptor |
| Function | mGluR3 is a presynaptic autoreceptor and postsynaptic receptor that |
| Primary Expression | Brain (cortex, hippocampus, basal ganglia), glial cells |
| Subcellular Localization | Presynaptic membrane, postsynaptic density |
| Molecular Weight | 98 kDa (879 aa) |
| Amino Acids | 879 aa |
| Pathways | MAPK, PI3K, NF-κB |
| UniProt ID | Q14832 |
| NCBI Gene ID | 2915 |
| Ensembl ID | ENSG00000138821 |
| OMIM | 604099 |
| GeneCards | GRM3 |
| Human Protein Atlas | GRM3 |
| Associated Diseases | ALS, Aging, Alzheimer, Bipolar, Depression |
| Interactions | GRM4, SYNGR1, GRIN2B, NCAM1, NRG1, RGS4 |
| KG Connections | 128 knowledge graph edges |
| Databases | GeneCardsHPASTRING |