GRM4

Understanding Entity Pages

This page aggregates everything SciDEX knows about GRM4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

GRM4 is a gene implicated in neurodegeneration research. Key relationships include: associated with, regulates, interacts with. Associated with ALS, Als, Bipolar. Connected to 65 entities in the SciDEX knowledge graph.

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graph TD
    GRM4["<b>GRM4</b>"]
    miR_29b_3p["miR-29b-3p"]
    GRM4 -->|"regulates"| miR_29b_3p
    NPDC1["NPDC1"]
    GRM4 -->|"interacts with"| NPDC1
    IL23["IL23"]
    GRM4 -->|"regulates"| IL23
    CBX4["CBX4"]
    GRM4 -->|"interacts with"| CBX4
    Prognosis["Prognosis"]
    GRM4 -->|"associated with"| Prognosis
    Schizophrenia{"Schizophrenia"}
    GRM4 -->|"associated with"| Schizophrenia
    Als{"Als"}
    GRM4 -->|"associated with"| Als
    Depression{"Depression"}
    GRM4 -->|"associated with"| Depression
    Bipolar{"Bipolar"}
    GRM4 -->|"associated with"| Bipolar
    Ms{"Ms"}
    GRM4 -->|"associated with"| Ms
    ALS{"ALS"}
    GRM4 -->|"associated with"| ALS
    SYNGR1["SYNGR1"]
    GRM4 -->|"associated with"| SYNGR1
    ADX88178["ADX88178"]
    ADX88178 -->|"activates"| GRM4
    rs2229901["rs2229901"]
    rs2229901 -->|"associated with"| GRM4
    circGrm4["circGrm4"]
    circGrm4 -->|"regulates"| GRM4
    Aspartame["Aspartame"]
    Aspartame -->|"upregulates"| GRM4
    LSP2_9166["LSP2-9166"]
    LSP2_9166 -->|"activates"| GRM4
    HTR2A["HTR2A"]
    HTR2A -->|"associated with"| GRM4
    DISC1["DISC1"]
    DISC1 -->|"associated with"| GRM4
    FKBP5["FKBP5"]
    FKBP5 -->|"associated with"| GRM4
    NRG1["NRG1"]
    NRG1 -->|"associated with"| GRM4
    DAO["DAO"]
    DAO -->|"associated with"| GRM4
    BMAL1["BMAL1"]
    BMAL1 -->|"associated with"| GRM4
    HTTLPR["HTTLPR"]
    HTTLPR -->|"associated with"| GRM4
    style GRM4 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0