DAO

Understanding Entity Pages

This page aggregates everything SciDEX knows about DAO: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

D-Amino Acid Oxidase - enzyme critical for D-serine metabolism and NMDA receptor signaling, implicated in ALS, schizophrenia, and neurodegenerative diseases

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graph TD
    DAO["<b>DAO</b>"]
    Schizophrenia{"Schizophrenia"}
    DAO -->|"associated with"| Schizophrenia
    Als{"Als"}
    DAO -->|"associated with"| Als
    Depression{"Depression"}
    DAO -->|"associated with"| Depression
    Bipolar{"Bipolar"}
    DAO -->|"associated with"| Bipolar
    Ms{"Ms"}
    DAO -->|"associated with"| Ms
    ALS{"ALS"}
    DAO -->|"associated with"| ALS
    BMAL1["BMAL1"]
    DAO -->|"associated with"| BMAL1
    GRM4["GRM4"]
    DAO -->|"associated with"| GRM4
    SYNGR1["SYNGR1"]
    DAO -->|"associated with"| SYNGR1
    BDNF["BDNF"]
    DAO -->|"associated with"| BDNF
    NCAM1["NCAM1"]
    DAO -->|"associated with"| NCAM1
    RGS4["RGS4"]
    DAO -->|"associated with"| RGS4
    HTR2A["HTR2A"]
    HTR2A -->|"associated with"| DAO
    DISC1["DISC1"]
    DISC1 -->|"associated with"| DAO
    FKBP5["FKBP5"]
    FKBP5 -->|"associated with"| DAO
    NRG1["NRG1"]
    NRG1 -->|"associated with"| DAO
    HTTLPR["HTTLPR"]
    HTTLPR -->|"associated with"| DAO
    MITOCHONDRIAL_DNA["MITOCHONDRIAL DNA"]
    MITOCHONDRIAL_DNA -->|"associated with"| DAO
    BDNF -->|"associated with"| DAO
    PERIOD3["PERIOD3"]
    PERIOD3 -->|"associated with"| DAO
    GRM4 -->|"associated with"| DAO
    G72["G72"]
    G72 -->|"associated with"| DAO
    TRPM2["TRPM2"]
    TRPM2 -->|"associated with"| DAO
    GENES["GENES"]
    GENES -->|"associated with"| DAO
    style DAO fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0