| Gene Symbol | HSPA1A |
| Full Name | Heat Shock Protein Family A (Hsp70) Member 1A/1B |
| Aliases | HSP70PROTEIN |
| Chromosome | 6p21.33 (HSPA1A), 6p21.33 (HSPA1B) |
| Protein Family | Heat shock protein 70 family (HSP70 superfamily) |
| Protein Type | Chaperone |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Primary Expression | Cytoplasm, nucleus (stress-induced) |
| Subcellular Localization | </strong></td><td>Cytosol, nucleus, endoplasmic reticulum, mitochondria</td></tr> |
| Molecular Weight | 70 kDa |
| Amino Acids | 640 aa |
| Pathways | Akt, Apoptosis, Chaperone, Complement, Epithelial-Mesenchymal Transition |
| UniProt ID | P0DMV8 |
| OMIM | 140100 |
| GeneCards | HSPA1A |
| Human Protein Atlas | HSPA1A |
| Associated Diseases | ALS, Alzheimer, Cancer, Lung Cancer, Ms |
| Known Drugs/Compounds | tRNA, 5S rRNA, Trna, 5S Rrna, Non-Coding Rna, aducanumab |
| Interactions | TFE3, MAP1LC3A, MLKL, DEPTOR, HMGB1, EGF |
| KG Connections | 1134 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |