| Gene Symbol | PIK3R1 |
| Full Name | Phosphoinositide-3-Kinase Regulatory Subunit 1 |
| Aliases | p85α, PI3K-p85, GRB1 |
| Chromosome | 5q13.1 |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 85 kDa |
| Amino Acids | 724 aa |
| Pathways | PI3K, mTOR, mtor, PI3K pathway |
| GeneCards | PIK3R1 |
| Human Protein Atlas | PIK3R1 |
| Protein Class | PI3K regulatory subunit (SH2 domain-containing) |
| PIK3CA (p110α) | Catalytic subunit |
| PTEN | Negative regulator |
| IRS1/2 | Substrate |
| GRB2 | Adapter protein |
| Associated Diseases | ALS, Aging, Alzheimer, Cancer, Fibrosis |
| Interactions | SRC, MTOR, IGF1, CDK1, QSOX1, LAMB2 |
| KG Connections | 382 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |