protein 740 words KG: LGALS1PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

LGALS1 Protein — Galectin-1

🔬 Protein Info
Gene SymbolLGALS1
Full NameGalectin-1
AliasesLGALS1PROTEIN
Chromosome22q13.1
FunctionLGALS1 performs diverse biological functions:
Amino Acids135 aa
PathwaysMapk
GeneCardsLGALS1
Human Protein AtlasLGALS1
Cell TypeExpression Level
[Neurons](/entities/neurons)High (specific subtypes)
[Astrocytes](/entities/astrocytes)High
[Microglia](/entities/microglia)Moderate
Schwann CellsHigh
Immune CellsVariable (activation-dependent)
Associated DiseasesAls, Ms
InteractionsJAK2, GNB4, HSP90B1, EGFR, HSPA4, FOXO1
KG Connections89 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (3)

Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51
Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42
Designer TRAK1-KIF5 fusion proteins accelerate therapeutic m
Score: 0.35

Related Analyses (6)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived
RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived

Related Experiments (23)

Cytochrome Therapeutics
clinical · proposed · Score: 0.40
s:** - Single-cell RNA-seq to measure editing efficiency acr
falsification · proposed · Score: 0.40
Metabolic Pathway-Targeted Therapy in ALS
clinical · proposed · Score: 0.40
ALS Progression Rate Heterogeneity — mechanism and biomarker
clinical · proposed · Score: 0.40
ALS Regional Onset and Spread: Network-Level Staging Model
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in