| Gene Symbol | NF1 |
| Full Name | Neurofibromin 1 |
| Chromosome | 17q11.2 |
| Protein Family | Ras GTPase-activating protein (Ras-GAP) family |
| Function | encodes a large tumor suppressor protein that negatively regulates the Ras signaling pathway. |
| Primary Expression | the nervous system: |
| Subcellular Localization | Cytoplasm, Membrane-associated, Nucleus |
| Molecular Weight | 327 kDa (2,818 amino acids) |
| Amino Acids | 818 aa |
| Exons | 60 |
| Pathways | MAPK signaling |
| UniProt ID | P21359 |
| Ensembl ID | ENSG00000196712 |
| OMIM | 613113 |
| GeneCards | NF1 |
| Human Protein Atlas | NF1 |
| Associated Diseases | ALS, Cancer, Epilepsy, Glioblastoma, Glioma |
| Interactions | TERT, CDK4, NRAS, POT1, AKT, MTOR |
| KG Connections | 265 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |