protein 980 words KG: NPC2PROTEIN 2026-03-21
kind:proteinsection:proteinsstate:published
Contents

NPC2 Protein — Niemann-Pick C2 Protein

🔬 Protein Info
Gene SymbolNPC2
Full NameNPC intracellular cholesterol transporter 2
Chromosome14q11.2
Protein FamilyNPC2 family
FunctionNPC2 encodes a small lysosomal cholesterol transport protein (Niemann-Pick disease, type C2).
Subcellular LocalizationLysosome, late endosome
Molecular Weight~17 kDa (151 amino acids)
Amino Acids151 aa
PathwaysCholesterol
UniProt IDO15148
NCBI Gene ID10577
Ensembl IDENSG00000119655
OMIM607015
GeneCardsNPC2
Human Protein AtlasNPC2
Associated DiseasesAls, Diabetes, Parkinson's disease, Type 2 Diabetes, disease, frontotemporal dementia
InteractionsTREM2, TFEB, Actin, APOE, PLIN2, SOAT1
KG Connections44 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph