| Gene Symbol | NR4A1PROTEIN |
| Chromosome | 12p13.31 |
| Protein Type | Receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 64 kDa |
| Amino Acids | 598 aa |
| Exons | 7 |
| GeneCards | NR4A1PROTEIN |
| Human Protein Atlas | NR4A1PROTEIN |
| Approach | Mechanism |
| Nur77 agonists | Activate protective gene programs |
| Gene therapy | Overexpress Nur77 in neurons |
| Small molecule modulators | Enhance Nur77 stability/activity |
| Combination therapy | Nur77 + neurotrophic factors |
| Associated Diseases | Aging, Als, Inflammation, Ms, Neurodegeneration |
| Interactions | P62, MDM2, JUN, ARC, PI3K, AKT |
| KG Connections | 126 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |