| Gene Symbol | P2RX1PROTEIN |
| Protein Type | Channel |
| Function | is a member of the P2X family of ATP-gated ion channels, encoded by the P2RX1 gene. |
| Primary Expression | smooth muscle, platelets, and certain neuronal populations |
| Amino Acids | 399 aa |
| GeneCards | P2RX1PROTEIN |
| Human Protein Atlas | P2RX1PROTEIN |
| N-terminal extracellular domain | ATP binding site with conserved motifs |
| Two transmembrane domains | TM1 and TM2 forming the pore |
| C-terminal intracellular domain | Short regulatory tail |
| Conserved cysteine residues | Form disulfide bonds for structural stability |
| Associated Diseases | Als, Inflammation |
| Interactions | adora2b, ADORA2B, ADRA2A, ALDH1A2, F3, GENES |
| KG Connections | 81 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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