| Gene Symbol | P2RX1PROTEIN |
| Protein Type | Channel |
| Function | is a member of the P2X family of ATP-gated ion channels, encoded by the P2RX1 gene. |
| Primary Expression | smooth muscle, platelets, and certain neuronal populations |
| Amino Acids | 399 aa |
| GeneCards | P2RX1PROTEIN |
| Human Protein Atlas | P2RX1PROTEIN |
| Subunit size | ~399 amino acids |
| Ion selectivity | Non-selective cation channel |
| Permeability | Na+, K+, Ca2+ (high Ca2+ permeability) |
| ATP EC50 | ~1-10 uM |
| Desensitization | Very fast (milliseconds) |
| Associated Diseases | ALS, Inflammation |
| Interactions | P2RX4, P2RX7, P2RY1, P2RX5, PANX1, P2RY12 |
| KG Connections | 83 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |