| Gene Symbol | PLAU |
| Aliases | uPA, urokinase, ATF |
| Chromosome | 10q22.2 |
| Protein Family | Serine protease family |
| Protein Type | Protease |
| Function | is a gene encoding a secreted serine protease that plays critical roles in fibrinolysis, extracellular matrix (ECM) remodeling, and cell migration. |
| Subcellular Localization | Extracellular, cell surface |
| Molecular Weight | 52 kDa (pro-uPA), 33 kDa (active) |
| Amino Acids | 411 aa |
| Exons | 11 |
| Pathways | TGF-β |
| UniProt ID | P00750 |
| NCBI Gene ID | 5328 |
| GeneCards | PLAU |
| Human Protein Atlas | PLAU |
| Associated Diseases | Als, Alzheimer, Leukemia, Ms |
| Interactions | CXCL10, CX3CL1, VIM, BDNF, FGF23, FGF21 |
| KG Connections | 175 knowledge graph edges |
| Databases | GeneCardsHPASTRING |