protein 790 words KG: S100BPROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

S100B Protein

🔬 Protein Info
Gene SymbolS100B
Full NameS100 Calcium Binding Protein B
AliasesS100BPROTEIN
Chromosome21q22.3
Protein FamilyS100 EF-hand calcium binding proteins
Functionis a gene encoding a calcium-binding protein of the S100 family, playing crucial roles in neuronal function, astrocyte biology, and neuroinflammation.
Molecular Weight10.5 kDa
Amino Acids92 aa
PathwaysPI3K
UniProt ID[P16401](https://www.uniprot.org/uniprot/P16401)
Ensembl IDENSG00000122574
OMIM176990
GeneCardsS100B
Human Protein AtlasS100B
ApproachStatus
Associated DiseasesAls, Cardiovascular, Glioma, Inflammation, Ms, Neurodegeneration
InteractionsC1Q, TGM2, GPNMB, HMGB1, APP, GFAP
KG Connections366 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

Knowledge Graph

Related Hypotheses (18)

Astrocyte-Mediated Microglial Memory Erasure
Score: 0.46
Aquaporin-4 Polarization Enhancement via TREK-1 Channel Modu
Score: 0.44
Glial Glycocalyx Remodeling Therapy
Score: 0.41
Transglutaminase-2 Cross-Linking Inhibition Strategy
Score: 0.49
Low Complexity Domain Cross-Linking Inhibition
Score: 0.42

Related Analyses (8)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Mitochondrial transfer between astrocytes and neurons
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
4R-tau strain-specific spreading patterns in PSP vs CBD
neurodegeneration · archived
Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in