| Gene Symbol | SREBF1 (SREBP1) |
| Full Name | Sterol Regulatory Element-Binding Protein 1 |
| Chromosome | 17p11.2 |
| Protein Family | SREBP Transcription Factor Family |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | ER (precursor), Golgi (processing), Nucleus (active) |
| Molecular Weight | 125 kDa (precursor), 60 kDa (active fragment) |
| Pathways | NF-κB |
| UniProt ID | P36956 |
| NCBI Gene ID | 6720 |
| Ensembl ID | ENSG00000172318 |
| OMIM | 184756 |
| Gene | SREBF1 |
| Associated Diseases | AD, ADH, ALS, AMI, Aging |
| Known Drugs/Compounds | rapamycin |
| Interactions | PSEN2, A2M, MAPT, PARP1, PEN2, PSEN1 |
| KG Connections | 612 knowledge graph edges |
| Databases | GeneCardsHPASTRING |