| Gene Symbol | SREBP1 |
| Aliases | Sterol Regulatory Element-Binding Protein 1 |
| Function | Regulatory Element-Binding Protein 1) |
| Molecular Weight | 125 kDa |
| Amino Acids | 480 aa |
| Pathways | Fatty Acid Synthesis, Cholesterol Synthesis, Lipid Metabolism, Mtor, Cholesterol |
| GeneCards | SREBP1 |
| Human Protein Atlas | SREBP1 |
| Isoform | Amino Acids |
| SREBP-1a | 1124 aa |
| SREBP-1c | 906 aa |
| SREBP-1a ΔN (isoform) | ~900 aa |
| Gene Variant | Effect |
| SREBF1 variants | Altered regulation |
| SREBP1 expression | Modified lipogenesis |
| Associated Diseases | Als, Carcinoma, Hepatocellular Carcinoma, Neurodegeneration, cancer, ferroptosis |
| Known Drugs/Compounds | Nobiletin, rapamycin, NOBILETIN |
| Interactions | PTEN, PI3K, SCD1, MTOR, AKT, LC3 |
| KG Connections | 214 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |