protein 1,329 words KG: TIMM23PROTEIN 2026-03-22
kind:proteinsection:proteinsstate:published
Contents

TIMM23 Protein — Translocase of Inner Mitochondrial Membrane 23

🔬 Protein Info
Gene SymbolTIMM23
Full NameTranslocase of Inner Mitochondrial Membrane 23
AliasesTIMM23PROTEIN
Chromosome10q11.21.
Protein FamilyTim23 family
FunctionThe TIM23 complex operates in conjunction with the TOM (Translocase of Outer Mitochondrial Membrane) complex, which recognizes and imports precursor proteins across the outer membrane.
Primary ExpressionHigh in brain, heart, muscle, kidney
Subcellular LocalizationMitochondrial inner membrane
Molecular Weight16 kDa
Amino Acids222 aa
PathwaysMitophagy
UniProt IDO00231
NCBI Gene ID10098
Ensembl IDENSG00000132268
GeneCardsTIMM23
Human Protein AtlasTIMM23
Associated DiseasesParkinson
InteractionsCALCOCO2, PARKIN, PRKN, NDP52, HSPD1, MTOR
KG Connections85 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Related Hypotheses (17)

AMPK hypersensitivity in astrocytes creates enhanced mitocho
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Membrane Cholesterol Gradient Modulators
Score: 0.52
Near-infrared light therapy stimulates COX4-dependent mitoch
Score: 0.51
Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51

Related Analyses (14)

TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived
Astrocyte reactivity subtypes in neurodegeneration
neurodegeneration · archived
Autophagy-lysosome pathway convergence across neurodegenerat
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived

Related Experiments (1)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40

See Also (1)

Neurodegeneration
disease · KG edge: implicated_in